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A (brief) blood-soaked history<p>Our ancestors accustomed little about blood. Alike the best basal of claret ability — claret central the anatomy is good, claret alfresco is not ideal, too abundant claret alfresco is account for affair — able humanity’s butt for an awkward cardinal of centuries.</p> <p>Absence this knowledge, our ancestors devised less-than-scientific theories as to what claret was, theories that assorted berserk beyond time and culture. To aces aloof one, the physicians of Shakespeare’s day believed claret to be one of four actual fluids or “humors” (the others actuality atramentous bile, chicken bile, and phlegm).</p> <p>Handed bottomward from age-old Greek physicians,<a href=”https://www.nlm.nih.gov/exhibition/shakespeare/fourhumors.html” target=”_blank”> humorism</a> declared that these actual fluids bent someone’s personality. Claret was advised hot and moist, consistent in a sanguine temperament. The added claret a actuality had in his system, the added passionate, charismatic, and abrupt he would be. Teenagers were advised to accept a accustomed affluence of blood, and men had added than women.1</p> <p>Humorism advance to all sorts of poor medical advice. Best famously, Galen of Pergamum acclimated it as the base for his decree of bloodletting. Sporting a “when in doubt, let it out” mentality, Galen declared claret the ascendant humor, and bloodletting an accomplished way to antithesis the body. 2 Blood’s affiliation to calefaction additionally fabricated it a go-to for agitation reduction.</p> <p>While bloodletting remained accustomed until able-bodied into the 19th century,2 William Harvey’s assay of the apportionment of claret in 1628 would put anesthetic on its aisle to avant-garde hematology.</p> <p>Soon afterwards Harvey’s discovery, the ancient claret transfusions were attempted, but it wasn’t until 1665 that aboriginal acknowledged admixture was performed by British physician Richard Lower. 3 Lower’s operation was amid dogs, and his success prompted physicians like Jean-Baptiste Denis to try to alloy claret from animals to humans, a action alleged xenotransfusion. The afterlife of beastly patients ultimately led to the convenance actuality outlawed.4</p> <p>The aboriginal acknowledged human-to-human admixture wouldn’t be performed until 1818, back British obstetrician James Blundell managed it to amusement postpartum hemorrhage. 3 But alike with a authentic address in place, in the afterward decades abounding blood-transfusion patients connected to die mysteriously.</p> <p>Enter<a href=”https://www.nobelprize.org/nobel_prizes/medicine/laureates/1930/landsteiner-bio.html” target=”_blank”> Austrian physician Karl Landsteiner</a>. In 1901 he began his assignment to allocate claret groups. Exploring the assignment of Leonard Landois — the physiologist who showed that back the red claret beef of one beastly

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